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Pathogenesis and therapy of amyotrophic lateral sclerosis

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Published by Lippincott-Raven in Philadelphia .
Written in English


  • Amyotrophic lateral sclerosis.

Book details:

Edition Notes

StatementGeorges Serratrice.
SeriesAdvances in neurology
The Physical Object
Paginationxx, 290 p. :
Number of Pages290
ID Numbers
Open LibraryOL22751863M
ISBN 100781703336

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Pathophysiology of Amyotrophic Lateral Sclerosis. By Fabian H. Rossi, Maria Clara Franco and Alvaro G. Estevez. Submitted: May 9th Reviewed: April 17th Cited by: 2. Amyotrophic lateral sclerosis (ALS) is a progressive disease of the voluntary motor system with clinical signs of both lower and upper motor-neuron compromise (Haverkamp et al., ). Weakness and muscle atrophy usually begin asymmetrically and distally in one limb, spread within the neuraxis to involve contiguous groups of motor neurons, and Cited by: 1. INTRODUCTION: Amyotrophic lateral sclerosis (ALS) or motor neuron disease is a rapidly progressive neurodegenerative disorder. The primary involvement is of motor neurons in the brain, spinal cord and peripherally. There is secondary weakness of muscles and primary involvement of other brain regions, especially involving by: Amyotrophic lateral sclerosis (ALS) is a devastating paralytic disorder caused by motor neuron degeneration. A subgroup of familial cases arises from mutations in the gene encoding cytosolic.

Amyotrophic lateral sclerosis (ALS) is the most common degenerative disease of the motor neuron system. Although ALS is incurable and fatal, with median survival of 3 years, treatment can extend the length and meaningful quality of life for patients. Signs and symptoms. In % of patients, symptoms begin with limb involvement. Initial. An overriding mystery of ALS pathogenesis orbits around the molecular basis of selective motor neuron vulnerability and clouds our view. There are likely mechanisms involved in the initiation of motor neuron loss and mechanisms involved in the progression of motor neuron loss once initiated. Motor neuron vulnerability is likely related to the unique biological characteristics of these : Laura Ferraiuolo. 32 rows  Though considerable amount of research, both pre-clinical and clinical, has been conducted . Amyotrophic Lateral Sclerosis Pathogenesis: A Journey Through the Secretory Pathway Article Literature Review (PDF Available) in Antioxidants & Redox Signaling 13(12) December

  Amyotrophic Lateral Sclerosis summarises this new information. The editors are experts in the subject, and they have assembled an international collection of authors—59 of them, from 11 countries in four continents. Obviously, being an edited collection with several contributors, this book is replete with the problems common to all such Author: Carlo Colosimo. Amyotrophic Lateral Sclerosis -- diagnosis. Amyotrophic Lateral Sclerosis -- therapy. Form/Genre: Congress. Kongreß -- Marseille -- Konferenzschrift -- -- Marseille. Contents: 1. Overview of the Pathogenesis and Therapy of Amyotrophic Lateral Sclerosis / Georges T. Serratrice and Theodore L. Munsat 2. Excitotoxic Mechanisms in the.   Amyotrophic lateral sclerosis (ALS), degenerative neurological disorder that causes muscle atrophy and paralysis. The disease usually occurs after age 40; it affects men more often than women. ALS is frequently called Lou Gehrig disease in memory of the famous baseball player Lou Gehrig, who died.   Today we'll be talking about the pathogenesis and cell biology of the neurodegenerative disorder Amyotrophic Lateral Sclerosis, ALS. The fundamental feature of ALS is that it's characterized by the degeneration of both upper and lower motor neurons.